<%@LANGUAGE="JAVASCRIPT" CODEPAGE="1252"%> Orwig Laboratory-Publications
Transgenic Core Facility: Magee-Womens Research Institute University of Pittsburgh
 
 

Cover Photo- Copyright 2003 Elsevier Science   Cover Photo- Copyright 2003 Elsevier Science (Click for enlarged view)  Cover Photo- Copyright 2003, Biology of Reproduction (Click for enlarged view)  Cover Photo- Copyright 2001 National Academy of Sciences, U.S.A. (Click for enlarged view)  Cover Photo- Copyright 2001 National Academy of Sciences, U.S.A. (Click for enlarged view)  Cover Photo- Copyright 2000 National Academy of Sciences, U.S.A. (Click for enlarged view)

  1. B.P. Hermann, M. Sukhwani, M.C. Hansel, K.E. Orwig. 2010. Spermatogonial stem cells in higher primates: are there differences from those in rodents? Reproduction 139: 479–493; DOI: 10.1530/REP-09-0255 [ABSTRACT]
  2. Y. Sheng, C.C. Lin, J. Yue, M. Sukhwani, J.J. Shuttleworth, T. Chu, K.E. Orwig. Generation and characterization of a Tet-On (rtTA-M2) transgenic rat. 2010. BMC Developmental Biology, 10:17. [ABSTRACT]
  3. B.P. Hermann, M. Sukhwani, D.R. Simorangkir, T. Chu, T.M. Plant, K.E. Orwig. 2009. Molecular Dissection of the Male Germ Cell Lineage Identifies Putative Spermatoganial Stem Cells in Rhesus Macaques. Hum Reprod. 24(7): 1704-16. [PUBMED]
  4. R. Escamilla-Hernandez, L. Little-Ihrig, K.E. Orwig , J. Yue, U. Chandran, A.J. Zeleznik. 2008. Constitutively Active Protein Kinase A Qualitatively Mimics the Effects of Follicle-Stimulating Hormone on Granulosa Cell Differentiation. Mol Endocrinol. 22(8):1842-52. [PUBMED]
  5. K.E. Orwig, B.Y. Ryu, S. Master, B.T. Phillips, M. Mack, M.R. Avarbock, R.L. Brinster. 2008. Genes Involved in Post-transcriptional Regulation are Over Represented in Stem/progenitor Spermatogonia of Cryptorchid Mouse Testes. Stem Cells. 26(4):927-38. [PUBMED]
  6. J. Yue, Y. Sheng, K.E. Orwig. 2008. Identification of Novel Homologous microRNA Genes in the Rhesus Macaque Genome. BMC Genomics. 9(1): 8. [PUBMED]
  7. B.P. Hermann, M. Sukhwani, C.C. Lin, Y. Sheng, J. Tomko, M. Rodriguez, J.J. Shuttleworth, D. McFarland, R.M. Hobbs, P.P. Pandolfi, G.P. Schatten, K.E. Orwig. 2007. Characterization, Cryopreservation and Ablation of Spermatogonial Stem Cells In Adult Rhesus Macaques. Stem Cells 25(9):2330-2338. [PUBMED]
  8. Navara CS, Mich-Basso JD, Redinger CJ, Ben-Yehudah A, Jacoby E, Kovkarova-Naumovski E, Sukhwani M, Orwig K, Kaminski N, Castro CA, Simerly CR, Schatten G. 2007. Pedigreed Primate Embryonic Stem Cells, Express Homogeneous Familial Gene Profiles. Stem Cells. 25(11):2695-704. [PUBMED]
  9. B.Y. Ryu, K.E. Orwig, J.M. Oatley, C.C. Lin, L.J. Chang, M.R. Avarbock, R.L. Brinster. 2007. Efficient Generation of Transgenic Rats Through the Male Germline using Lentiviral Transduction and Transplantation of Spermatogonial Stem Cells. J Androl. 28(2):353-60. [PUBMED]
  10. B.Y. Ryu, K.E. Orwig, J.M. Oatley, M.R. Avarbock, R.L. Brinster. 2006. Effects of Aging and Niche Microenvironment on Spermatogonial Stem Cell Self-Renewal.  Stem Cells. 24(6):1505-1511. [PUBMED]
  11. A. Buageaw, M. Sukhwani, A. Ben-Yehudah, J Ehmcke, VY Rawe, C Pholpramool, K.E. Orwig, S. Schlatt. 2005. GDNF Family Receptor alpha1 Phenotype of Spermatogonial Stem Cells in Immature Mouse Testes. Biol. Reprod. 73(5):1011-1016. [PUBMED]
  12. K.E. Orwig, S. Schlatt. 2005. Cryopreservation and transplantation of spermatogonia and testicular tissue for preservation of male fertility.
    J Natl Cancer Inst Monogr. 34:51-56. [PUBMED]
  13. B.Y Ryu, K.E. Orwig, H. Kubota, M.R. Avarbock, R.L. Brinster. 2004. Phenotypic and functional characteristics of spermatogonial stem cells in rats. Dev. Biol. 274:158-170. [PUBMED]
  14. J.A. Costoya , R.M. Hobbs, M. Barna, G. Cattoretti, K. Manova,
    M. Sukhwani, K.E. Orwig, D.J. Wolgemuth, P.P. Pandolfi. 2004. Essential role of Plzf in maintenance of spermatogonial stem cells. Nature Genetics. 36: 653-659. [PUBMED]
  15. B.Y. Ryu, K.E. Orwig, M.R. Avarbock, R.L. Brinster. 2003. Stem cell and niche development in the postnatal rat testis. Dev. Biol. 263:253-263. [PUBMED]
  16. T. Shinohara, K.E. Orwig, M.R. Avarbock, R.L. Brinster. 2003. Restoration of spermatogenesis in infertile mice by Sertoli cell transplantation. Biol. Reprod. 68:1064-1071. [PUBMED]
  17. C.J. Brinster, B.-Y. Ryu, L. Karagenc, R.L. Brinster, K.E. Orwig. 2003. Restoration of fertility by germ cell transplantation requires effective recipient preparation. Biol. Reprod. 69:412-420. [PUBMED]
  18. K.E. Orwig, B.-Y. Ryu, M.R. Avarbock, R.L. Brinster. 2002. Male germ-line stem cell potential is predicted by morphology of cells in neonatal rat testes. Proc. Nat. Acad. Sci. USA. 99:11706-11711. [PUBMED]
  19. K.E. Orwig, M.R. Avarbock, R.L. Brinster. 2002. Retrovirus-mediated modification of male germline stem cells in rats. Biol. Reprod. 67:874-879. [PUBMED]
  20. T. Shinohara, K.E. Orwig, M.R. Avarbock, R.L. Brinster. 2002. Germ line stem cell competition in postnatal mouse testes. Biol. Reprod. 66:1491-1497. [PUBMED]
  21. K.E. Orwig, T. Shinohara, M.R. Avarbock, R.L. Brinster. 2002. Functional analysis of stem cells in the adult rat testis. Biol. Reprod. 66:944-949. [PUBMED]
  22. M. Nagano, C.J. Brinster, K.E. Orwig, B.-Y. Ryu, M.R. Avarbock, R.L. Brinster. 2001. Transgenic mice produced by retroviral transduction of male germ-line stem cells. Proc. Nat. Acad. Sci. USA. 98:13090-13095. [PUBMED]
  23. T. Shinohara, K.E. Orwig, M.R. Avarbock, R.L. Brinster. 2001. Remodeling of the postnatal mouse testis is accompanied by dramatic changes in stem cell number and niche accessibility. Proc. Nat. Acad. Sci. USA. 98:6186-6191. [PUBMED]
  24. T. Shinohara, K.E. Orwig, M.R. Avarbock, R.L. Brinster. 2000. Spermatogonial stem cell enrichment by multiparameter selection of mouse testis cells. Proc. Nat. Acad. Sci. USA. 97:8346-8351. [PUBMED]
  25. S. Filley, S. Supansic, U. Salli, K. Orwig, F. Stormshak. 2000. Myristoylated alanine-rich c kinase substrate protein and mRNA in bovine corpus luteum during the estrous cycle. Endocrine 12:289-294. [PUBMED]
  26. K.E. Orwig and M.J. Soares. 1999. Transcriptional activation of the decidual/trophoblast prolactin-related protein gene. Endocrinology. 140:4032-4039. [PUBMED]
  27. G.D. Dai, B.M. Chapman, B. Liu, K.E. Orwig, D. Wang, R.A. White, B. Preuett, M.M. Soares. 1998. A new member of the mouse prolactin (PRL)-like protein-C subfamily, PRL-like protein-Ca: Structure and Expression. Endocrinology 139:5157-5163. [PUBMED]
  28. K.E. Orwig, M.W. Wolfe, C.B. Cohick, G. Dai, T.J. Peters, M.J. Soares. 1998. Trophoblast-specific regulation of endocrine-related genes. Trophoblast Research 12:65-85.
  29. H. Müller, K.E. Orwig, M.J. Soares. 1998. Identification of two new members of the mouse prolactin gene family. Biochim. Biophys. Acta 1396:251-258. [PUBMED]
  30. M.J. Soares, H. Müller, K.E. Orwig, T.J. Peters, G. Dai. 1998. The Uteroplacental prolactin family and pregnancy. Biol. Reprod. 58:273-284. [PUBMED]
  31. H. Müller, R. Ishimura, K.E. Orwig, B. Liu, M.J. Soares. 1998. Homologues for prolactin-like protein-A and B are present in the mouse. Biol. Reprod. 58:45-51. [PUBMED]
  32. K.E. Orwig, R. Ishimura, H. Müller, B. Liu and M.J. Soares. 1997. Identification and characterization of a mouse homolog for decidual/trophoblast prolactin-related protein. Endocrinology 138:5511-5517. [PUBMED]
  33. K.E. Orwig, C.A. Rasmussen and M.J. Soares. 1997. Decidual Signals in the establishment of pregnancy: the prolactin family. Trophoblast Research 10:329-343.
  34. K.E. Orwig, G. Dai, C.A. Rasmussen and M.J. Soares. 1997. Decidual/trophoblast prolactin-related protein: characterization of gene structure and cell-specific expression. Endocrinology 138:2491-2500. [PUBMED]
  35. C.A. Rasmussen, K.E. Orwig, S. Vellucci and M.J. Soares. 1997. Dual expression of prolactin-related protein in decidua and trophoblast tissues during pregnancy. Biol. Reprod. 56:647-654. [PUBMED]
  36. C.A. Rasmussen, K. Hashizume, K.E. Orwig, L. Xu and M.J. Soares. 1996. Decidual prolactin-related protein: heterologous expression and characterization. Endocrinology 137:5558-5566. [PUBMED]
  37. M.J. Soares, B.M. Chapman, C.B. Cohick, C.A. Rasmussen, G. Dai, T. Kamei and K.E. Orwig. 1996. Differentiation of trophoblast endocrine cells. Placenta 17:277-289. [PUBMED]
  38. F. Stormshak, K.E. Orwig and J.E. Bertrand. 1995. Dynamics of molecular mechanisms underlying ovarian oxytocin secretion. Journal of Reproduction and Fertility. 49:379-390. [PUBMED]
  39. K.E. Orwig, J.E. Bertrand, B.-R.Ou, N.E. Forsberg and F. Stormshak. 1994. Immunochemical characterization and cellular distribution of protein kinase C isozymes in the bovine corpus luteum. Comparative Biochemistry and Physiology. 108B:53-57. [PUBMED]
  40. K.E. Orwig, J.E. Bertrand, B.-R.Ou, N.E. Forsberg and F.Stormshak. 1994. Involvement of protein kinase C, calpains and calpastatin in prostaglandin F2*-induced oxytocin secretion from the bovine corpus luteum. Endocrinology. 134:78-83. [PUBMED]
  41. K.E. Orwig, S. Leers-Sucheta, M.F. Moghaddam, Z.D. Jiang, W.R. Gerwick and F. Stormshak. 1992. Unique metabolites of eicosapentaenoic acid interfere with corpus luteum function in the ewe. Prostaglandins. 44:519-530. [PUBMED]

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Last Modified: 17-Feb-2010
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